A review published in 2022 in the journal NanoImpact evaluated the latest research related to genotoxic effects of titanium dioxide through in vivo studies and in vitro cell tests. Researchers summarized the results by stating TiO2 nanoparticles “could induce genotoxicity prior to cytotoxicity,” and “are likely to be genotoxic to humans.”

It doesn’t take much to imagine what they must be doing to our poor skin each day as we layer on our sunscreen, foundation, concealers, eyeshadows & lip sticks which all contain large doses of titanium dioxide.

In a study published in the journal Toxicology, researchers examined the effects of exposing human colon cancer cell line (HTC116) titanium dioxide food additives in vitro. “In the absence of cytotoxicity, E171 was accumulated in the cells after 24 hours of exposure, increasing granularity and reactive oxygen species, inducing alterations in the molecular pattern of nucleic acids and lipids, and causing nuclei enlargement, DNA damage and tubulin depolymerization,” the scientists wrote. Researchers removed the additive from the culture, then examined the results 48 hours later. They found, “The removal of E171 was unable to revert the alterations found after 24 h of exposure in colon cells. In conclusion, exposure to E171 causes alterations that cannot be reverted after 48 h if E171 is removed from colon cells.”

Titanium dioxide is often listed in the ingredients list on the product label when used in home, beauty and personal care products.

Exposure to titanium dioxide in utero and in breastfeeding children

Overall, the use of TiO2 in factory settings plays a crucial role in enhancing the quality, performance, and appearance of a wide range of products. Its unique properties make it an invaluable ingredient in various industrial processes, allowing manufacturers to create high-quality, durable, and visually appealing finishes. As technology continues to advance, the demand for TiO2 is expected to grow, further solidifying its importance in the manufacturing industry.

Thanks to its rheological and optical properties, Lithopone offers both technical and economic advantages wherever organic and inorganic binder systems require a relatively high pigmentation for specific applications.

States looking to ban titanium dioxide as a food additive

The FDA's Code of Federal Regulations allows for the legal, regulated use of titanium dioxide in food products, under some restrictions.

In cosmetics, titanium dioxide’s properties enhance coloration and can help protect skin from damaging UVA and UVB rays.

What exactly is titanium dioxide?

Studies have been carried out with both emulsion paints and powder paints, both with clear results on how the use of lithopone supplier 30% reduces the appearance of algae in the paint once it has been applied (see photos). 

Lithopone

How can I tell if a product has titanium dioxide in it? How can I avoid the ingredient?